
A cozy ground beef and pasta casserole combines creamy Alfredo sauce with tender penne and melty cheese for an easy weeknight dinner.
My family requests this dish regularly - the combination of pasta and seasoned beef in creamy sauce creates the ultimate comfort meal.
Essential Ingredients:
- Lean ground beef: Provides hearty base
- Penne pasta: Holds sauce well
- Quality Alfredo sauce: Use preferred brand
- Mozzarella: Creates perfect melt
- Fresh Parmesan: Adds sharp flavor
- Italian seasoning: Enhances sauce
- Fresh garlic: Deepens flavor

Detailed Instructions:
- Prepare Components
- Boil pasta 1 minute under al dente
- Brown beef until no pink remains
- Season meat with spices
- Use oven-safe skillet if possible
- Build Casserole
- Mix beef with Alfredo sauce
- Add half the mozzarella
- Fold in drained pasta
- Spread evenly
- Add Cheese Layer
- Top with remaining mozzarella
- Sprinkle with Parmesan
- Create even coverage
- Press slightly into pasta
- Bake Until Bubbly
- Heat through completely
- Watch for golden spots
- Broil briefly if desired
- Rest before serving
- Rest before serving
Properly seasoning the beef and choosing a good Alfredo sauce makes all the difference in flavor.
Storage Tips:
Keeps 3-4 days refrigerated. Reheat gently with splash of milk.
Perfect Pairings:
Serve with garlic bread and simple green salad.

Chef's Tips:
- Season each component
- Grate cheese fresh
- Watch broiler carefully
- Check seasoning before baking
Years of making casseroles taught me that layering flavors and proper pasta cooking creates the perfect comfort food dish.
Frequently Asked Questions
- → Can I prepare ahead?
- Assemble up to 2 days ahead. Add 10 minutes bake time.
- → What pasta shape works?
- Any short pasta like ziti or rotini.
- → Jar sauce substitutes?
- Use homemade Alfredo or bechamel sauce.
- → How to store leftovers?
- Keep refrigerated up to 3 days. Reheat in oven.
- → Can I add vegetables?
- Add broccoli, mushrooms, or spinach.